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Home > Archives > Volume 20, No 11 (2022) > Article

DOI: 10.14704/nq.2022.20.11.NQ66341

Phytochemical and Pharmacological evaluation of anti-inflammatory activity in isolated compounds from “Balanite aegyptiaca”

Gaurav Goyanar*, Nirmal Dongre, Raghvendra Dubey, Hemant Swami

Abstract

Different animal models were used to test the anti-inflammatory effect of chemicals derived from Balanites aegyptiaca extract. One of the incredibly potent neglected wild plant species, Balanites aegyptiaca is primarily found in the deserts of South Asia and Africa. Due to its ability to treat a variety of fatal diseases, this elegant and historical folkloric medicine is traditionally used to treat a wide range of conditions, including jaundice, wound healing, malaria, syphilis, epilepsy, constipation, diarrhoea. It is known that various plant parts are used in folklore medicines to cure a variety of illnesses. N-Hexane was used to obtain the extract from the dried seeds of Balanites aegyptiaca by the process of maceration. Obtained extract was analysed for the presence of various phytochemical constituents and further isolated to obtain the active constituents responsible for anti- inflammatory activity. Isolation of compound conducted using isocratic elution technique in column chromatography and characterized using IR and NMR spectroscopy.

Keywords

Balanites aegyptiaca, Anti-inflammatory activity, Isocratic elution, Isolation, Standardization

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