Introduction- Parkinson's disease is a progressive neurological disorder that results in significant socioeconomic repercussions for individuals, their families, and society at large. The aim of present study is to evaluate the clinico-epidemiological profile of Parkinson's disease patients visiting a tertiary care hospital. Material and methods- The hospital based observational cross-sectional study was conducted at ESIC Medical College and Hospital, Alwar, Rajasthan among patients of parkinsonian disease during the study period of August 2024 to May 2025. Convenient sampling method was used and a total of 250 patients of PD diagnosed by a neurologist or those who were admitted or attended neurology and medicine OPD were selected. The demographic data and clinical signs and symptoms were recorded. Hoehn and Yahr scale was used to assess the severity at presentation. Results- The majority of patients were aged >70 years (38%), with a male predominance (65.2%). The majority originated from urban regions (58.8%) and were classified among the lower medium (36.8%) and higher lower (28.4%) socioeconomic strata. The majority had a duration of Parkinson's disease ranging from 1 to 3 years (38.8%). Tremor was the predominant presenting symptom (57.2%), with a higher incidence of right-sided onset (52.8%). Approximately 48% of patients exhibited early stages (I–II), and the remainder were in moderate to late stages (III–V). There is a statistically significant association (p<0.0001) between disease duration and clinical staging (Hoehn & Yahr). Conclusion- The clinical characteristics of PD patients in the current study were comparable to those observed in other populations in India and other developing nations. The produced data may facilitate enhancements in Parkinson's disease diagnosis and the formulation of more patient-centered, outcome-oriented treatment strategies.

Clinical, Epidemiological, Hoehn and Yahr, Parkinson’s Disease