Background: Peters anomaly is a rare congenital ocular condition characterized by central corneal opacity and anterior segment dysgenesis. Type 2 Peters anomaly, distinguished by the presence of corneolenticular adhesions and cataracts, is less frequently reported and often associated with systemic anomalies. Case Presentation: We report a rare case of bilateral Peters anomaly type 2 in a female baby born out of non-consanguineous marriage to a primi mother at 26 weeks of gestation. Fundoscopy done showed bilateral corneal opacity with central thinning part with suspected iridocorneal adhesions. B scan showed bilateral Peters anomaly type II with bilateral micro-ophthalmia and left anterior keratoconus. Genetic workup for PAX6 and other genes related for above diagnosis was advised. Conclusion: This case highlights the phenotypic complexity of Peters anomaly type 2 and underlines the importance of early multidisciplinary evaluation, including genetic analysis and systemic screening, to guide appropriate management and prognosis.

Peters anomaly, glaucoma, corneal opacity, Descemet's membrane, penetrating keratoplasty.