Background: Pseudoexfoliation syndrome (PES) is an age-related progressive accumulation and deposition of fibrillar protein material over various tissues. About 50% of patients with exfoliation syndrome are diagnosed with glaucoma, whether it is found at the time of initial examination or at a later date. PES syndrome accounts for 15-20% of open angle glaucoma cases. PES leads to a serious clinical course and worse prognosis than Primary open angle glaucoma. Glaucoma with pseudoexfoliation has poor response to medications, more severe clinical courses and more necessity of surgical interventions. Objective: to identify and document the risk factors amongst patients presenting with PEX for Secondary Glaucoma. Method: this Cross Sectional Observation study was carried out in a tertiary care teaching hospital in Ahmedabad, Gujarat, India. All patients with pseudoexfoliation syndrome presenting in the Ophthalmology OPD during the study period of July 2019 to March 2020 were included in the present study. Patients underwent detailed ocular examination including intraocular pressure, gonioscopy measurement. Results: The majority of the subjects in the present study were more than between the ages 66-70 years with the mean age of 60.9. In the present study 55.4% patients were female while 44.6% were male,indicating females are more prone for developing pseudoexfoliation syndrome. Conclusion: It was evident from the present study that Pseudoexfoliation does act as a risk factor in the form of pseudoexfoliation material deposits in several structures of the eye which eventually leads to rise in intraocular pressure and development of secondary glaucoma. Pseudoexfoliation syndrome is definitely a risk factor for the development of glaucoma.

Pseudoexfoliation, Glaucoma, Intraocular pressure, gonioscopy