Pollution of the Saryu River has forced microorganisms that live there to develop protective survival mechanisms. This study identified and characterized heavy metal-resistant bacteria from the Saryu River. Water and sediment samples were taken from six locations along the river. The pH, turbidity, salinity, temperature, and dissolved oxygen levels were determined in situ. The amounts of six heavy metals (Cd, Cu, Fe, Ni, Pb, and Zn) in the water samples were measured using atomic absorption spectroscopy. Growth investigations were conducted utilizing isolation methods. The uppermost section of the Saryu River with the lowest pH has the largest concentrations of heavy metals. Turbidity, salinity, and specific conductivity increased significantly at Site 4. MIC testing revealed that 16 isolates had strong iron and lead resistance.

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