Development Of In -Situ Gel For Ocular Drug Delivery

Volume 24 No 7 (2026)

Tonduru Aruna Kumari, Kranthi, Praveen Guijula, D.Raghava, Kavala Nageswara Rao

DOI: 10.48047/nq.2026.24.7. NQ27032

Abstract

Background: Conventional ophthalmic solutions suffer from poor bioavailability due to rapid precorneal drainage, necessitating frequent administration and potentially causing patient non compliance. In-situ gelling systems offer a promising approach by transforming from solution to gel upon ocular administration, thereby prolonging drug residence time

Keywords

In-situ gel, Ocular drug delivery, Poloxamer, Carbomer, Gellan gum

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