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Volume 14 No 3 (2016)
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Comparison of Urine Acetoacetic Acid and Capillary Beta Hydroxybutyrate in the Diagnosis and Management of Diabetic Ketoacidosis: A Prospective Observational Study from a Tertiary Care Hospital
Dr.Subash Kumar T, Dr.Annitha Elavarasi J, Srinivasan R
Abstract
Background
Diabetic ketoacidosis (DKA) is a life-threatening acute metabolic complication of
diabetes mellitus characterized by hyperglycemia, ketosis, and metabolic acidosis.
Conventional diagnosis relies on urine ketone testing using nitroprusside reaction,
which detects acetoacetate but not β-hydroxybutyrate (β-OHB), the predominant ketone
body during DKA. Early diagnosis and monitoring are crucial for reducing morbidity and
mortality.
Keywords
Diabetic ketoacidosis, β-hydroxybutyrate, urine ketones, acetoacetate, diabetes mellitus, capillary ketone testing.
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