Background: Achieving hemodynamic stability during anesthetic induction is essential to minimize perioperative complications. Both sevoflurane (inhalational) and propofol (intravenous) are commonly used agents for induction before laryngeal mask airway (LMA) insertion. This study was designed to compare their effects on hemodynamic parameters. Methods: A prospective, randomized controlled trial was conducted on 104 ASA I–II adult patients scheduled for elective surgeries under general anesthesia. Participants were randomized into two groups: Group S (sevoflurane via vital capacity induction [VCI]) and Group P (IV propofol 2 mg/kg). Heart rate, systolic blood pressure (SBP), diastolic blood pressure (DBP), and mean arterial pressure (MAP) were recorded at baseline, post- induction, and post-LMA insertion. Results: The propofol group demonstrated a significant decline in SBP, DBP, and MAP post- induction and post-LMA insertion (p < 0.05), while the sevoflurane group maintained more stable hemodynamic profiles. Heart rate fluctuations were minimal in both groups. Conclusion: Sevoflurane offers better cardiovascular stability during induction and LMA insertion, making it a preferable agent in patients with compromised cardiovascular function.

Sevoflurane, Propofol, Hemodynamic Stability, Laryngeal Mask Airway, Vital Capacity Induction