Background: Chronic kidney disease (CKD) is a progressive disorder characterized by irreversible loss of renal function and is associated with substantial morbidity and mortality. Increasing evidence suggests that oxidative stress plays a crucial role in the pathogenesis and progression of CKD. Imbalance between reactive oxygen species production and antioxidant defense mechanisms contributes to renal injury, inflammation, and cardiovascular complications. Evaluation of oxidative stress biomarkers may provide valuable insights into disease severity and progression. Objectives: To assess oxidative stress markers in patients with chronic kidney disease and to determine their association with renal function parameters.

Chronic kidney disease; Oxidative stress; Malondialdehyde; Superoxide dismutase; Reduced glutathione; Renal function; Chronic renal failure