Volume 2 No 2 (2004)
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A study of neuro-ophthalmic manifestations of intracranial space occupying lesions
Dr. Minati Kumari Devi, Dr. Baig Abbas Ali
Abstract
Current study is to analyze various Neuro-ophthalmic features of intracranial tumours. A prospective observational study on the various Neuro- ophthalmic manifestations of intracranial tumours and their visual prognosis to treatment. The study was carried out in 48 patients who were proven to have Brain tumours clinically and radiologically presented to the Department of ophthalmology. The mean age of patients affected by Brain tumour was 39.53 years. There is a slight Male preponderance. Defective vision is the most common presentation. Headache and Giddiness. follow after. Multiple cranial nerves were affected in 9 patients. Nystagmus was observed in 5%, Pendular nystagmus being the most common variant. Field defect was found in 56.7% of cases.Sellar and suprasellar tumours compress the visual pathway and the most common presentation is Temporal pallor followed by Primary optic atrophy. Posterior fossa tumours present with papilledema while Secondary optic atrophy is seen in late cases. Central nervous system disturbances like altered sensorium, gait disturbance and Rombergism were seen in some patients of posterior fossa tumours. Pituitary adenomas comprise the majority (45.8%) of intra cranial tumours with ophthalmic manifestations, followed by meningiomas with an incidence of 22.9%.Pituitary macroadenoma presents with ocular features as it compresses the visual pathway. The visual prognosis is poor in case of pituitary macroadenomas. There was a statistically significant association between BCVA at presentation and follow up BCVA (p<0.001). Thus, the visual prognosis depends upon the vision at presentation.
Keywords
neuro-ophthalmic manifestations, intracranial space, intracranial tumours, macroadenomas
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