DOI: 10.14704/nq.2019.17.5.2369

Differences in Neurobiology of Different Syndrome of Melancholia in the Viewpoint of TCM

Sun Fengli, Liu Jie, Chen Fengpei, Zhu Jianfeng, Gao Zhihan, Ren Zhibin, Shen Ying, Chen Zhenxin, Ma Yongchun, Wang Zhiqiang, Jin Weidong

Abstract


To some extent, melancholia in different Traditional Chinese Medicine (TCM) Syndromes represents different "subtypes" of depression. Whether bipolar depression or general depression, whether accompanied with or without psychotic symptoms, or with or without cognitive impairment, there are clinical and possible biological differences in these depressions, which indicates that different "subtypes" of depression represented by different TCM syndromes not only are different clinical syndromes, but also imply that there may be some biomarkers. The melancholia with liver depression and stagnation is different from melancholia with deficiency of both heart and spleen in clinical symptoms, which may indicate that there are differences in some potential biological biomarkers. For example, central nervous transmitters, trace elements, electrophysiology, neuroendocrinology, brain imaging, and even genomics may differ among different TCM syndrome types of depression, which not only serves for the modernization of TCM, but also finds biological differences for different TCM syndrome types of depression.

Keywords


depressions, TCM, neurobiology

Full Text:

PDF

References


Bao ZX, Tian Q, Chen BJ, Zhong YuF. Literature Discussion on the Relationship between Depression and Yang Qi Deficiency Syndrome in Traditional Chinese Medicine. Journal of Zhejiang University of Traditional Chinese Medicine 2011; 35(3): 466-467.

Camacho-Arroyo I, Hansberg-Pastor V, Gutiérrez-Rodríguez A, Chávez-Jiménez J, González-Morán MG. Expression of sex hormone receptors in the brain of male and female newly hatched chicks. Animal reproduction science 2018; 188: 123-129.

Cui Y and Zuan JQ. Discussion of relationship among depression, stress and TCM kindney, Shanghai Chinese Medicine University, 2011

Gao ZH and Jin WD. The study progresses of relationship between antidepressants and HPA function in depression. Herald of Medicine 2017; 36(6): 659-664.

Gao ZH, Zhu JF, Shen Y, Chen ZX, Chen J, Jin WD. Analysis of difference on HPA function and psychopathology between depressive patients with stagnation of liver Qi and deficiency of both heart and spleen. Zhejiang Journal of Traditional Chinese Medicine 2017; 52(5): 324-324.

Han Y, Du Y, Li BJ. Changes of Task State Brain Function in Depressive Patients with Liver Depression and Qi Stagnation and Deficiency of Heart and Spleen.13th National Symposium on Psychiatry with Integrated Traditional Chinese and Western Medicine, 2013.

Li XZ. Multivariate Analysis of Common TCM Syndrome Indicators of Depression and Preliminary Study on Serum BDNF Level. Central South University, 2004.

Li L, Xie H, Dai JF. Relationship between HPG and depression. Medicine Review 2014; 20(21): 3872-3874.

Lu XB, Chen DY, Yao Jianxin, Mu Man, Dang Yamei, Xue LQ, Yang MX. Effect of Chinese and Western Medicine on Depression and Its Impact on HPA, HPT and HPG Axis. Journal of Biomedial Engineering 2011; 8: 1265-1267.

Nie RR, Mo BW, Zeng WX. Effect of Acupuncture and Moxibustion on Serum 5-HT, NE and BDNF Levels in Patients with Post-stroke Depression. West Medicine 2017; 29(6): 808-812.

Shen Y and Wang W. Character of event-related potential P300 on depression of stagnation of liver Qi and deficiency of both heart and spleen. Zhejiang University, 2014.

Trine Stub and Jianping Liu. Acupuncture treatment for depression-A systematic review and meta-analysis. European Journal of Integrative Medicine 2011; 4(3): e259-270.

Xiao D and Huang C. Progress of Acupucture on function of HPG. TCM Information 1999; 23(1): 21-22.

Yang HM, Li YH, Yang J. Relationship between TCM Syndrome Differentiation and Neurotransmitter in Peripheral Blood of Depression. Chinese Journal Of Information on TCM 2011; 18(4): 14-16.

Zhang YF and Han Y. Analysis of Deficiency Syndrome and Empirical Diagnosis of Depression by Hydrogen Proton Spectrum of Magnetic Resonance.12th National Symposium on Psychiatry with Integrated Traditional Chinese and Western Medicine, 2013.

Zhang YF,Han Y,Zhang YZ. An Empirical Study of brain function connection in Resting State in depressive patients with sthenia and deficiency syndrome. Fifth China Sleep Medicine Forum 2013; pp. 122-128.


Supporting Agencies





| NeuroScience + QuantumPhysics> NeuroQuantology :: Copyright 2001-2019