: From Non-Living Matter to Quantum Neurobiology and Psychopathology

The concepts of quantum brain, quantum mind and quantum consciousness have been increasingly gaining currency in recent years, both in scientific papers and in the popular press. In fact, the concept of the quantum brain is a general framework. Included in it are basically four main sub-headings. These are often incorrectly used interchangeably. The first of these and the one which started the quantum mind/consciousness debate was the place of consciousness in the problem of measurement in quantum mechanics. Debate on the problem of quantum measurement and about the place of the conscious observer has lasted almost a century. One solution to this problem is that the participation of a conscious observer in the experiment will radically change our understanding of the universe and our relationship with the outside world. The second topic is that of quantum biology. This topic has become a popular field of research, especially in the last decade. It concerns whether or not the rules of quantum physics operate in biological structures. It has been shown in the latest research on photosynthesis, the sense of smell and magnetic direction finding in animals that the laws of quantum physics may operate in warm-wet-noisy biological structures. The third sub-heading is quantum neurobiology. This topic has not yet gained wide acceptance and is still in its early stages. Its primary purpose is directed to understand whether the laws of quantum physics are effective in the biology of the nervous system or not. A further step in brain neurobiology, towards the understanding of consciousness formation, is the research of quantum laws effects upon neural network functions. The fourth and final topic is quantum psychopathology. This topic takes its basis and its support from quantum neurobiology. It comes from the idea that if quantum physics is involved in the normal working of the brain, diseased conditions of the brain such as depression, anxiety, dementia, schizophrenia and hallucinations can be explained by quantum physical pathology. In this article, these topics will be reviewed in a general framework, and for the first time a general classification will be made for the quantum brain theory.

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Hi Sultan and Massimo,

Just a note to let you know that I read your very lucid and complete survey paper on quantum neurophysics in the International Journal of Psychophysiology. I want to express my appreciation for your hard work in summarizing and systematizing the major trends in this field. Your paper will be a valuable future resource to me and, I suspect, to many others in our community of investigators.

Thanks for your exceedingly helpful and penetrating achievement!

Best,

Don Mender



Thank you for this interesting reflexion on quantum neurobiology. This domain is still beyond the interest of most of neuroscientists. It is not so surprising if we consider the difficulty for each of us to enter unusual concepts and acquire new knowledges. However, as you suggest it, the persisting ignorance of quantum phenomena in the brain probably hinders major breakthroughs in the understanding of brain functioning and in the discovery of new treatments for neurological and psychological diseases. Let us hope it will change in a next future !
Sincerely,

Philippe Anglade.




.....great your article Sultan Tarlici. Thanks a lot!!

all the best, Ulrich

Dr. Ulrich Warnke
Bionik-Institut
c/o Internationales Bionikzentrum,
Science Park 2 an der Universität des Saarlandes,




I very much appreciate your sending this paper to me. I am reading it very carefully. I have a question: Is your attempts at classification your own point of view or are they garnered from the opinions of a group or physicists, cosmologists, psychologists etc? I have no problem with seeing your making clear the quantum field but am curious as a researcher how much I should depend on how you make these classifications. This is in no way suggesting I do not have the utmost respect for your insights. I am in the knowledge acquisition and knowledge management department of the Knowowlege Institute and Language Institute at Bangkok University and research data base acqusition strategies. Therefore, my question stems from the reliability to retrieve information in your attempts at classification areas. It seems to me there is a lot of cross over so I wonder how you deal with that aspect independent of the major classifications in bio. neuro psycho etc as prefixes.
Thanks for any time you give this query,
I am still reading your paper and very much enjoy your Journal

Willard Van De Bogart
Language Institute
Bangkok University




Dear Sultan,

Thanks for sending me your latest article on the above subject. I think this is a very good idea and helps to clarify a very difficult subject.
Some developments have recently taken place that I think you will find very interesting and that have a direct bearing on what you have laid out.
I will put this in the form of a tale, which may have a surprise ending.
The attachments I will be referencing will be sent to you via separate email.

Around 15 years ago I wrote a paper in which I proposed an experiment to determine if there are EPR nonlocal correlations between 2 neuron transistors. (Attch.1.) Very briefly, 2 spatially separated and shielded neuron transistors were utilized, with just one of them being subjected to electrical stimulation. We then wanted to see if the 2nd non-stimulated neuron transistor would become stimulated or fire due to nonlocal 'signal'
transmission from the stimulated neuron.

Several years later Prof. Rita Pizzi and her research group at the Univ.
of Milan conducted a much more sophisticated experiment in which they used
2 separated and shielded microelectrode arrays (MEAs) contining a large number of neurons on each MEA deerived from the same host. (Attch. 2.) They noticed some unusual electrical correlations between the stimulated and non-stimulated neurons which led her to believe that they were either observing some ultra-low electromagnetic effect or biological quantum nonlocality. It is her intention now to use Mu-metal shielding in her next round of experiments to rule in or out ultra-low EMF or nonlocality.
Either finding would be counterintuitive.

Now we fast forward to 2013, and a paper has been published from UCLA in which the researchers claim to have observed unusual cell-to-cell communication effects between separated and barely shielded cancer cells/primary sensory neurons but, not at the same stringent experimental protocol level as was observed by Rita. (Attch.3.) I immediately got in touch with them and informed them that such equivalent research had been performed several years before them, and that I had not seen any of this referenced in their paper. I also sent them copies of all the relevant earlier papers of myself and Rita. They apologised for this error but, I am naturally suspicious, as one can go to a number of search sites and pull up this information. Both Rita and I have suggested that in their forthcoming experiments that they use Mu-metal shielding, as this will rule out any ultra-low EMF effects, which they intend to do. The important thing here Sultan is that this was funded by the NIH!

So, it looks like some type of answer will be forthcoming as to part of this biological quantum nonlocal mystery in the near future. The problem will then be that we will probably see several people or groups come forward and claim to be the father(s) of such a discovery!

Best regards,

Fred Thaheld

Attch. 1. Proposed experiment to determine if there are EPR nonlocal correlations between two neuron transistors. F.H. Thaheld, 2000.

Attch. 2. Anomalous findings in cultured neurons in presence of laser pulses. R. Pizzi et al. 2008.

Attch. 3. Physically disconnected non-diffusible cell-to-cell communication between neuroblastoma SH-SY5Y and DRG primary sensory neurons. V. Chaban et al.




Dear Dr.Tarlaci,
Thank you for sending me your interesting paper. I have a quick look. I think following issues in this connection need to be addressed:
(1) Brain does not process information but also interpret it. So one needs to define what is meant by information measure in general in biological system particularly in brain. This is a challenging issue since information measure like Shannon or Fisher measure are not valid for biological systems.

We are seriously working on this issue.
(2) Quantum tunneling : several people like Beck and Eccles et al tried to use concept of tunneling.

However, the formalism of tunneling has been extended needs to be extended for open quantum system or dissipative quntum systems. Because tunneling through synapses are like tunneling in dissipative systems. Infact very recently one of my graduate students submitted his Ph.D. thesis worked out quantum tunneling for open quantum system. Ofcourse this is purely from the point of view of quantum physics. We are thinking of applying to real biological systems.

What do you think ?
Regards,
sisir roy




Dear Professors Tarlaci ans Pregnolato
Thank you for quoting my olfaction work in your article "Quantum Neurophysics”. I thought you might be interested in this recent paper which is perhaps closer to your focus of interest http://www.pnas.org/content/111/34/E3524.abstract

very best wishes

Luca



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