DOI: 10.14704/nq.2022.20.11.NQ66249

ALKALOIDS OF Annona muricata L

Sory FOFANA , Rikhsivoy ZIYAYEV , JAMSHID CHO’LIYEV .Olimjon PANJIEV

Abstract

The content of alkaloids in the leaves of Annona murikata L collected in the Republic of Guinea was studied for the first time. The extraction of the alkaloids was carried out in a conventional manner, separately on the leaves. The contents of gross total alkaloids extracted are particularly low in the leaves (0.125% by mass of the dried plant material). Separation of alkaloids was carried out by chromatography on silica columns. 9 alkaloids were isolated and identified from the leaves. The main isolated alkaloids are aporphinoids (aporphins, noraporphins, oxo-aporphins, dehydro-aporphine) and benzyltetrahydroisoquinolines. Isolated alkaloids have been identified by examining their spectral data and their physical constants; possible confirmation has been brought by comparison with genuine specimens. Alkaloids: anonaine (3), roemerine (4), azimylobine (5), isoboldine (8), and liriodenine (9) were identified by direct comparison with the control of each of these alkaloids previously isolated from Liriodendron tulipifera L (Magnoliaceae).

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