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Home > Archives > Volume 20, No 12 (2022) > Article

DOI: 10.14704/nq.2022.20.12.NQ77005

Design and evaluation of Azathioprine loaded flakes in cap for Colon Specificity

KHUSHBOO JASRA1*, AMANDEEP SINGH2, KANCHAN SINGH3, NEELAM PAINULY4

Abstract

Colonic delivery refers to targeted delivery of drugs into the lower GI tract, which occurs primarily in the large intestine (i.e. colon). Colonic delivery refers to targeted delivery of drugs in the lower GI tract, this occurs primarily in the large intestine (i.e. colon). Colonic delivery refers to targeted delivery of drugs into the lower GI tract, which occurs primarily in the large intestine (i.e. colon). Colonic delivery refers to targeted delivery of drugs into the lower GI tract, which occurs primarily in the large intestine (i.e. colon). Azathioprine is an immunosuppressant, that is, a drug that is used to suppress the immune system. The present investigation concerns the development of mouth dissolving tablet of azathioprine which were designed colon specificity. flakes of azathioprine were formulated using polymers namely black mustard, yellow mustard, sorghum, ragi, pectin, guar gum carried out studies for Weight variation., Hardness., Friability, Uniformity of weight, Water absorption ratio, Wetting time, Disintegration test and in-vitro dissolution study.

Keywords

Colonic delivery, Azathioprine, Immunosuppressant

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