DOI: 10.14704/NQ.2022.20.11.NQ66291

Nanoemulsion as a new advanced technology of drug delivery system

Mariam Saleem, Mowafaq Ghareeb

Abstract

Nanoemulsions (also called mini-emulsions, ultrafine emulsions, and submicron emulsions) are reviewed and summarized. The droplet sizes of nanoemulsions typically vary from 20 to 200 nm, and their size distributions are very narrow. There has been a growing interest in the study of nanoemulsion formation via condensation or lowenergy emulsification methods, even though the great majority of publications on oil-in-water (O/W) or water-in-oil (W/O) nanoemulsions report their formation via dispersion or high-energy emulsification (based on the phase transitions that take place during the emulsification process). Nanoemulsions are resistant to sedimentation and creaming because their droplets are so small, and Ostwald ripening is the primary method by which they break down. Specifically, the use of nanoemulsions as formulations for controlled drug administration and targeting is the principal use of nanoemulsions that is seeing active development at the present time.

Keywords

Nanoemulsion, drug delivery system, nanoemulsion

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