DOI: 10.14704/nq.2022.20.11.NQ66272

IN-VITRO EVALUATION OF AN ANTI-FUNGAL NAIL LACQUER CONTAINING MICONAZOLE NITRATE

Jai Kishun, Ankur Srivastava, Vikash Chandra, Vishal Srivastava, Ravindra Singh, Navneet Kumar Verma

Abstract

The primary goal is the formulation and evaluation of an anti-fungal nail lacquer that contains miconazole nitrate and is intended to treat the skin condition known as onychomycosis, which is brought on by pathogens such as candida, dermatophytes, and non-dermatophytes. Nail lacquer is also useful for enhancing therapeutic effectiveness and ensuring patient compliance. It can be made by simply combining non-volatile ingredients and achieving the desired gloss, flow, and smoothness. Humans use nail lacquer on their fingernails and toenails. In order to enhance beauty, gloss, and colour, it is important to protect the nail and nail plate. In order to increase the topical absorption of the drug over the nail, nail lacquer is mostly utilised for medications with poor oral bioavailability. This preparation uses a variety of ingredients, including 2 hydroxy propyl beta cyclodextrin, ethyl cellulose, nitrocellulose, and propylene glycol, to construct the medicine and provide the best possible release.

Keywords

Fungal Infection, Nail Lacquer, Onychomycosis.

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