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Home > Archives > Volume 20, No 11 (2022) > Article

DOI: 10.14704/nq.2022.20.11.NQ66118

‘Deoxypyridinoline’- an important biomarker in gingival crevicular fluid and serum for alveolar bone loss in patients who have periodontitis: A clinical study

Dr. Dasari Vanditha, Dr. Pragyan Swain, Dr. Saswati Mohanty, Dr. Babita Pawar, Dr. Aishwarya Virendra Satpute, Dr. kirti karda, Dr Ravindra Soni

Abstract

Background: Several components of gingival crevicular fluid (GCF) give a pointer toward disease status and represent the course as well as the prediction of periodontal disease. Potential biomarkers such as deoxypyridinoline (DPD), a metallophosphoesterase, would correctly determine the presence of osteoclast-mediated bone turnover activity. Additionally, this metallophosphoesterase seems to hold great promise as a predictive marker to determine bone destruction and active phases in the progression of the disease.

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