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Home > Archives > Volume 20, No 8 (2022) > Article

DOI: 10.147042022/nq.20.8.NQ44958

The role of C-reactive protein in the diagnosis of preterm premature rupture of membrane

Roaa mahmood ahmed, Yossra saleh khudhur


Background:Preterm birth is the leading cause of neonatal mortality and morbidity in the developed countries. Preterm labor is also the most common reason for antenatal hospitalization of pregnant women, which is associated with socio-economical burdens to the society. Aim of the Study: The study aimed at evaluating the role of CRP in in the perdition of PPROM and PID in pregnant women Patients and methods: This is a comparative study that was conducted in the Department of Obstetrics and Gynecology of Salah Al-Din General Hospital from 1st of December 2021 through April 2022.The study included 50 pregnant women presented with PPROM and attending the department of Obstetrics and Gynecology who had Singleton viable pregnancy with a gestational age ranging from 28- 36+6 weeks depending on accurate last menstrual period and / or by early ultrasonography. They were informed about the nature of the study and verbal consent was obtained from them. The study also included 50 pregnant women without any complaint as control groups. Detailed history was obtained. General and systemic examinations were done. Blood samples collected from each subject enrolled in this study for determination of ESR, WBCs counts and C-reactive protein. Results:The study revealed that the mean of CRP was elevated significantly in women with PPROM (11.76 mg/dl) as compared with the control group (4.34 mg/dl) at P. value <0.05. The study also showed that the high mean of WBC and ESR recorded among PPROM women as compared with the control group.The study showed that, 40% of PPROM women in the current study were with short cervical length , 30% were with Low socioeconomic conditions, 30% with uterine overdistension, 20% with Previous preterm birth, 16% with Sexually transmitted infections, , 18% with Vaginal bleeding and 6% were Smoker. Conclusion:The study concluded that The study revealed that the mean of CRP, WBC and ESR recorded among PPROM women as compared with the control group.


PPRO: CRP; WBC;ESR; Pregnancy; Preterm.

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