DOI: 10.14704/nq.2022.20.8.NQ44932

EVALUATION OF REMINERALIZING POTENTIAL OF THREE DIFFERENT REMINERALIZING AGENTS ON ARTIFICIAL CARIOUS LESIONS: A COMPARATIVE STUDY

Patel Foram, Choksi Kaksha, Bhatt Rohan, Patel Megha, Patel Chhaya, Patel Nikhil

Abstract

Background: Invasive therapy of carious lesions initiates a cascade of re-treatment cycles with increasing loss of dental hard tissue. Non-invasive treatment using a remineralization system aims at delaying this cascade and has gained increasing attention. Aim: To evaluate the remineralization capability of CPP-ACP  Fluoride, Tricalcium Phosphate and xylitol herbal-based dentifrices on artificial carious lesion using Cariescan Pro device. Material and Method: Sixty extracted molars/premolars that satisfied the inclusion criteria were divided into four groups randomly: Group I-CPP-ACP  Fluoride, II- Tricalcium Phosphate, III- Xylitol herbalbased dentifrices and IV- Control Group. The samples were prepared and immersed in a bath of demineralizing solution for 96 hours to induce artificial carious lesions. Samples were than subjected to remineralizing agents daily for four minutes, washed with distilled water followed by storage in artificial saliva for 21 days. The evaluation of samples for remineralization was done using Cariescan PRO on the 7th, 14th and 21st day.Wilcoxon sign rank test was used for intragroup comparison whereas Kruskal-Wallis and Mann-Whitney test were used for intergroup comparison. Results: Group I (19.33±4.67) and group II (18.73±5.14) had significantly higher amount of remineralization potential when compared to group III (27.20±7.08) and control group at 21 days and was statistically significant (P< 0.001). Maximum remineralization was observed with Tricalcium Phosphate at 21 days (18.73±5.14). Conclusion: Considerable amount of remineralization of early carious lesions can be promoted by TCP and CPP-ACP-F. These are excellent delivery vehicles available in a slow release amorphous form to localize calcium, phosphate and fluoride at the tooth surface.

Keywords

Enamel Lesion,Tooth Remineralization, CPP-ACPF, Tricalcium Phosphate, Xylitol, Artificial Saliva, Cariscan Pro.

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