DOI: 10.14704/nq.2022.20.8.NQ44903

Evaluation of the Hematological Profile Levels in Iraqi Patients with Multiple Sclerosis

Sarah Abdulhameed Sahib, Ghassan Mohammad Sulaiman, Huda Jaber Waheed

Abstract

Multiple Sclerosis (MS) is a persistent progressive neurological disease of the central nervous system that attacks the myelinated axons. Discontinuous immune–moderate inflammatory alterations in the myelin sheath. The MS research community is very interested in characterizing the physiological variations seen in MS and its subtype, and some studies have shown the presence of cerebrospinal fluid and hematology-related biomarkers connected to multiple sclerosisstatus. The aim of the study detects the changing that happened in CBC tests in multiple sclerosis patients. MS patients (n=100) were divided into two groups; newly diagnosed (42), and patients with ongoing treatments (58). These groups were compared to healthy subjects (n=55); the mean age ±SD was (30±8.46 years), (37±8.06years), and (31±8.73 years) for MS newly patients, patients with ongoing treatments, and healthy subjects, respectively.hematological parameters (hemoglobin concentration (HB), packed cell volume (PCV), white blood cells (WBC), and platelet count (PLT) were evaluated by immediately analyzing entire blood for a complete blood picture using the fully automated analyzer Sysmex Xn 1000 hematology in Baghdad teaching hospital. the result of the current study was the hematological parameters did not differ significantly [Hb, PCV, WBC, and PLT] in MS patients group when compared to the control group.

Keywords

multiple sclerosis, Hematology, CBC.

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