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Home > Archives > Volume 20, No 7 (2022) > Article

DOI: 10.14704/nq.2022.20.7.NQ33350

Testing AMH as an indicator of ovarian response in assisted reproductive technologies

Suchitra Narayan, Purnima Pachori, Sandhya Choudhry, Mahima Agrawal

Abstract

Objective: To evaluate the AMH as a predictive marker of ovarian response in assisted reproductive technology outcome. Methods: 140 women (age 25–40 years) selected for in vitro fertilization treatment were included in this study. Analysis of day-2 serum samples was done for the AMH, FSH, Inhibin B, and LH by ELISA kit methods. USG was done for the antral follicle count (AFC) and oocytes’retrieval. Results: The mean AMH levels of all treated patients were 2.41 ± 0.310. ROC for the AMH indicating poor ovarian response with sensitivity of 74 % and specificity of 72 %.A statistically significant positive correlation was observed between the number of oocytes retrieved and the AMH (r = 0.598, p = 0.0041) (Fig. 2). Significant correlation was also seen between the number of oocytes retrieved and AFC (r = 0.390, p = 0.0026). Conclusion: Our data demonstrated that AMH is an adequate predictor of both high and poor ovarian response but it does not associate with pregnancy outcomes.

Keywords

Anti-Mullerian hormone, Antral follicle count, Oocytes retrieval count, assisted reproductive technology (ART)

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