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Home > Archives > Volume 20, No 7 (2022) > Article

DOI: 10.14704/nq.2022.20.7.NQ33076

Evaluation of Serum Apelin Levels in Postmenopausal Breast Cancer Women

Shaymaa Jamal Hussin, Nihad N. Hilal , Sura Zahim Hussein Name

Abstract

Cancer is an abnormal proliferation of cells in a tissue or organ that causes the cells to change their nature, eventually producing a lump or mass and spreading to other regions of the body in most cases. The aim of this study is to evaluate the serum level of apelin in postmenopausal breast cancer women patient and compared with control group. Serum samples were collected from 90 women were 30 of these women were control and 60 women were breast cancer patients attending to cancer center in Kirkuk city/ Iraq from November 2021 to April 2022. Postmenopausal breast cancer women ages were above 46 years, who were proved to be suffering from breast cancer whether a unilateral or bilateral breast affected who agree to participate in this study. The results showed increased the level of apelin in breast cancer women (2.18±0.66) ng/ml rather than control (0.19±0.10) ng/ml with a highly significant increase (P≤0.01) in total postmenopausal breast cancer women compare with healthy control. Elevated apelin levels are more common in metastatic breast cancer patients than with other tumor markers therefore, it is considered as a marker in breast cancer.

Keywords

Apelin, Breast cancer: Adipose tissue: Postmenopausal breast.

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