DOI: 10.14704/nq.2022.20.7.NQ33018

Study the Level of Cartilage Acidic protein (CRTAC1) in Serum of Iraqi Patients with osteoarthritis

Huda S. Mutar, Bushra F. Hasan, Samer abdulhasan muhi

Abstract

Osteoarthritis, often known as OA, is defined by the deterioration of articular cartilage, limited intraarticular inflammation with synovitis, and alterations in the peri-articular and subchondral bone. This study measured CRTAC1, CRP, ESR, Vitamin D3, Mg, Calcium, and Lipid profiles in Osteoarthritis patients. The current study comprised a total of 130 participants, who were divided into two groups. Group1 contained 90 Osteoarthritis patients, and group2 controls 40; the samples were extracted from female and man, the levels, CRTAC1, CRP, ESR , Vitamin D3 ,Mg, Calcium, Cholesterol, TG, VLDL, LDL, and HDL were evaluated. The levels of CRTAC1, CRP and , Vitamin D3 were determined using an enzyme-linked immunosorbent assay (ELISA), and the stories , Mg, Calcium , Cholesterol, TG, VLDL, LDL, and HDL were assayed using a Human Reader HS Device. Westergren method was used to analyze the level of ESR . The result of CRTAC1 shows a high significant change among two groups OA patients and control. Serum vitamin D3 and CRP value have high significant change in their levels in osteoarthritis patients. Serum levels of Triglyceride, HDL, Mg, Ca , ESR and VLDL showed a significant changes between two groups OA patient and control. Cholesterol and LDL values have non-significant variation in their levels in osteoarthritis patient's comparison with control.

Keywords

According to the presented results CRTAC1, CRP, ESR, Vitamin D3, Mg, Calcium, T.G, VLDL, and HDL do affect by Osteoarthritis patients. LDL and cholesterol do effect osteoarthritis patients

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