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Home > Archives > Volume 17, No 7 (2019) > Article

DOI: 10.14704/nq.2019.17.7.2591

Auditory and Visual Oddball Paradigm Evaluated Through P300 in Five Girls with Rett Syndrome

Rosa Angela Fabio, Tindara Capri, Caterina Buzzai, Virginia Pittala , Antonio Gangemi


Few studies investigated information processing in genetic syndrome, such as Rett Syndrome, using ERPs. The main aim of this study was to examine visual and auditory processes in children with Rett Syndrome through the oddball paradigm. Five children with a diagnosis of Rett Syndrome, ranging from 7 to 11 age (M = 8, 8 years, SD = 4,36), matched for sex, age and mental age to typically developing children. Event-related potentials were recorded to an auditory and visual oddball task in all participants. The results showed that both auditory and visual P300 latencies were longer in the Rett group than the typically developing group. These findings suggest that children with Rett Syndrome need more time to process information.


Rett Syndrome, ERP, oddball task, P300

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